Blog Spotlight #2

Blog Spotlight #2

Article: Human commensals producing a novel antibiotic impair pathogen colonization In a recent study by Zipperer et al., scientists discovered a new antibiotic called lugdunin that is derived from Staphylococcus lugdunensis. The peculiar and exciting part of this discovery is that Staphylococcus lugdunensis is found in human noses and would be one of the first examples of human commensal bacteria producing antibiotics (Zipperer et al. 2016). The pressure for new antibiotics is higher than ever because of the presence of antibiotic…

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MRSA Project

MRSA Project

For my upcoming project I will focus on MRSA and other antibiotic resistant forms of Staphylococcus aureus. I chose this class of bacterium because it is constantly in the news and scientific literature. This species of bacterium is one of the greatest potential threats humanity. With its ability to mutate rapidly against antibiotics and its ability to mutate between species this versatile and deadly bacterium is something humanity must learn to combat if we continue to flourish as a species….

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Blog Spotlight

Blog Spotlight

Introduction: Hepatocellular carcinoma (HCC) is one of the deadlier cancers in the world today, with a 5-year survival rate of 57% worldwide[1]. Although this cancer kills almost 600,000 people per year, there is only one drug on the market right now to fight this cancer[2]. This drug is called Sorafenib and it works by interfering with protein kinase signaling in cancerous cells and non-cancerous cell’s membranes[3]. The one major problem with this drug is that not only does it kill…

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Possible diseases

Possible diseases

Diseases to investigate   Leprosy is an infection caused by bacterium Mycobacterium leprae or Mycobacterium lepromatosis. Although it remains in the body for many years seemingly dormant, at some point in time the bacteria can become active and attack neurons, the respiratory tract, the skin and eyes. This can lead to granulomas of the nerves, loss of the sensation of pain, loss of body parts due to injury or decay and poor eye sight. There are treatments for leprosy which…

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Blog spotlight (practice)

Blog spotlight (practice)

Fatty Acid oxidation is crucial for many pathways and functions in the human body. The product of fatty acid oxidation, Acetyl-CoA, plays many vital roes in energy generation and biosynthesis of larger macromolecules. In the paper by Wong and his associates, they further investigate the role of fatty acid oxidation and Acetyl-CoA in the formation of lymphatic endothelial cells (LEC). This research primarily focuses on the role of CPT-1 (Carnitine palmitoyl-transferase 1) which converts Acetyl-CoA into fatty acyl-carnitine which it…

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Why I want to become a Biochemist?

Why I want to become a Biochemist?

When I was younger, I really liked animals. I was always spending time with my dad watching people like Steve Erwin and Jeff Corwin. I really admired these great men during my childhood and felt a calling to go out and save animals/the earth from global warming. This led me to aspire to become a world-renowned zoologist. As I got older, I started to lose interest in animals and realized that zoology isn’t the most monetarily sustainable career. I began…

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